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Article

Nonviral genetic modification mediates effective transgene expression and functional RNA interference in human mesenchymal stem cells

11 Feb 2005

Abstract excerpt

BACKGROUND: Human mesenchymal stem cells (hMSC) are increasingly the focus of both basic and clinical research due to their ability to strike a balance between self-renewal and commitment to mesodermal differentiation. However, the promising therapeutic utility of hMSC in regenerative medical approaches requires detailed knowledge about their molecular characteristics. Therefore, genetic modification of hMSC...

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PMID: 15712343
DOI: 10.1002/jgm.731

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