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Article

Vasopressin-induced differential stimulation of AQP4 splice variants regulates the in-membrane assembly of orthogonal arrays.

American journal of physiology. Renal physiology - 1 Jun 2009

Van Hoek Alfred N, Bouley Richard, Lu Yingxian, Silberstein Claudia, Brown Dennis, Wax Martin B, Patil Rajkumar V

Abstract excerpt

Aquaporin-4 (AQP4) is a basolateral water channel in collecting duct principal cells and assembles into orthogonal array particles (OAPs), the size of which appears to depend on relative expression levels of AQP4 splice variants. Because the higher-order organization of AQP4 was perturbed by vasopressin in Brattleboro rats and phosphorylation sites have been identified on AQP4, we investigated whether vasopressin...

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Identifiers

PMID: 19297454
DOI: 10.1152/ajprenal.00018.2009
PMCID: PMC2692439

Genes

AQP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Vasopressin-induced differential stimulation of AQP4 splice variants regulates the in-membrane assembly of orthogonal arrays.PMID 19297454Read ↗

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