Get ready to Wnt: prepatterning in neuromuscular junction formation.

doi:10.1016/j.devcel.2009.03.001

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Article

Get ready to Wnt: prepatterning in neuromuscular junction formation.

Developmental cell - 1 Mar 2009

Zhang Bin, Xiong Wen C, Mei Lin

Abstract excerpt

Clustering of acetylcholine receptors (AChR) in muscle fibers prior to innervation by motor neurons is thought to be involved in neuromuscular junction formation. Jing et al. now report in Neuron that this prepatterning of AChRs, via a novel MuSK-dependent Wnt pathway, may guide motor axons to the central region of muscle fibers for synapse formation in zebrafish.

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Share to Mammals
Share to Body Patterning
Share to Models, Neurological
Share to Neuromuscular Junction
Share to Receptor Protein-Tyrosine Kinases
Share to Receptors, Cholinergic
Share to Receptors, LDL
Share to Wnt Proteins

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Identifiers

PMID: 19289078
DOI: 10.1016/j.devcel.2009.03.001
PMCID: PMC4214859

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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