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Article

Mutational analysis of Smad7 in human cervical cancer.

Oncology reports - 1 Apr 2009

Hariharan Ramkumar, Babu Janki Mohan, P Rema, Pillai M Radhakrishna

Abstract excerpt

Our aim was to carry out mutational analysis of Smad7 exon 4 that codes for the Smad7 MH2 domain in human cervical cancer tissues. This study is warranted since genetic abnormalities of components of the transforming growth factor-beta (TGF-beta)/Smad signaling system have been implicated in a variety of human cancers. Further, Smad7 is an important member of the Smad family that functions as a negative feedback...

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Identifiers

PMID: 19288000
DOI: 10.3892/or_00000315

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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