Article
Mechanism for Sortase Localization and the Role of Sortase Localization in Efficient Pilus Assembly in <i>Enterococcus faecalis</i>
14 Mar 2009
Abstract excerpt
Pathogenic streptococci and enterococci primarily rely on the conserved secretory (Sec) pathway for the translocation and secretion of virulence factors out of the cell. Since many secreted virulence factors in gram-positive organisms are subsequently attached to the bacterial cell surface via sortase enzymes, we sought to investigate the spatial relationship between secretion and cell wall attachment in...
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