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Article

Multiplex fluorescent PCR for noninvasive prenatal detection of fetal-derived paternally inherited diseases using circulatory fetal DNA in maternal plasma.

European journal of obstetrics, gynecology, and reproductive biology - 1 May 2009

Tang Dong-ling, Li Yan, Zhou Xin, Li Xia, Zheng Fang

Abstract excerpt

OBJECTIVE: To develop a fluorescent polymerase chain reaction (PCR) assay for the detection of circulating fetal DNA in maternal plasma and use the established multiplex in noninvasive prenatal genetic diagnosis and its further applications in forensic casework. STUDY DESIGN: The DNA template was extracted from 47 pregnant women and the whole blood samples from the stated biological fathers were used to detect...

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Identifiers

PMID: 19285775
DOI: 10.1016/j.ejogrb.2009.02.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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