Article
Potentially effective method for fetal gender determination by noninvasive prenatal testing for X-linked disease.
Congenital anomalies - 1 May 2019
Noda Yoshiteru, Kato Takema, Kato Asuka, Nishizawa Haruki, Miyazaki Jun, Ito Mayuko, Terasawa Sumire, Sekiya Takao, Fujii Takuma, Kurahashi Hiroki
Abstract excerpt
Examination of maternal plasma cell-free DNA (cfDNA) for noninvasive prenatal testing for fetal trisomy is a highly effective method for pregnant women at high risk. This can be also applied to fetal gender determination in female carriers of severe X-linked disease. Polymerase chain reaction (PCR) analysis is a relatively simpler and less expensive method of detecting Y chromosome-specific repeats (Y-specific...
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