Article
A prospective analysis of cell-free fetal DNA concentration in maternal plasma as an indicator for adverse pregnancy outcome.
Prenatal diagnosis - 1 Sept 2006
Bauer Margit, Hutterer Georg, Eder Martina, Majer Sandra, Leshane Erik, Johnson Kirby L, Peter Inga, Bianchi Diana W, Pertl Barbara
Abstract excerpt
OBJECTIVES: To evaluate whether cell-free fetal (cff) DNA in maternal plasma during the second trimester is a marker for developing pregnancy-associated complications. Two PCR techniques for the detection and quantitation of fetal DNA were compared. METHODS: Plasma samples were prospectively collected from 84 pregnant women carrying male fetuses before amniocentesis (14-29 weeks). We later recorded 26 pregnancies...
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