Article
Fetal sex identification in maternal plasma by means of short tandem repeats on chromosome x.
Annals of the New York Academy of Sciences - 1 Aug 2008
Vecchione Gennaro, Tomaiuolo Michela, Sarno Michelina, Colaizzo Donatella, Petraroli Rosella, Matteo Maria, Greco Pantaleo, Grandone Elvira, Margaglione Maurizio
Abstract excerpt
Analysis of fetal DNA in maternal plasma has recently been introduced as a new method for noninvasive prenatal diagnosis. In the majority of cases, the Y chromosome-specific sequences are commonly used as a fetus-specific marker with a high risk of false-negative cases. We attempted to develop a sensitive and reliable X chromosome short tandem repeat (STR) multiplex PCR amplification system that is suitable for...
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