Article
Regulation and function of neuronal GTP-Ras in facial motor nerve regeneration.
Journal of neurochemistry - 1 Mar 2009
Makwana Milan, Serchov Tsvetan, Hristova Mariya, Bohatschek Marion, Gschwendtner Andreas, Kalla Roger, Liu Zhiqiang, Heumann Rolf, Raivich Genndij
Abstract excerpt
Activation of Ras into the GTP-binding, 'ON' state is a key switch in the neurotrophin-mediated neuronal survival and neurite outgrowth, in vitro as well as in vivo. In the current study we explored changes in GTP-Ras levels following facial nerve injury and the ensuing regeneration and the effec...
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