Article
Neurocognitive endophenotypes in a multiplex multigenerational family study of schizophrenia.
The American journal of psychiatry - 1 May 2007
Gur Raquel E, Nimgaonkar Vishwajit L, Almasy Laura, Calkins Monica E, Ragland J Daniel, Pogue-Geile Michael F, Kanes Stephen, Blangero John, Gur Ruben C
Abstract excerpt
OBJECTIVE: Genetic factors contribute to the development of schizophrenia where cognitive dysfunction is a hallmark. The purpose of this article was to examine computerized neurocognitive measures as candidate endophenotypic markers of liability for schizophrenia in a genetically informative cohort. METHOD: European Americans from 35 multiplex multigenerational families (N=349) and healthy participants (N=154)...
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