Genetic polymorphism of glutathione S-transferase P1 gene and lung cancer risk.

doi:10.1023/a:1008811824890

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Article

Genetic polymorphism of glutathione S-transferase P1 gene and lung cancer risk.

Cancer causes & control : CCC - 1 Feb 1999

To-Figueras J, Gené M, Gómez-Catalán J, Piqué E, Borrego N, Carrasco J L, Ramón J, Corbella J

Abstract excerpt

OBJECTIVES: The human GSTTP1 gene is polymorphic with an A-->G transition in exon 5 causing a replacement 105 Ile-->Val in the GSTP1 protein. The two isoforms, encoded by the alleles GSTP1*A and GSTP1*B, respectively, show different catalytic efficiencies towards some carcinogenic epoxides. In this study we have addressed the possible role of the Ile105Val GSTP1 polymorphism in lung cancer susceptibility....

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Identifiers

PMID: 10334644
DOI: 10.1023/a:1008811824890

Genes

GSTP1
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.