Article
Identification of distinct ciprofloxacin susceptibility in Acinetobacter spp. by detection of the gyrA gene mutation using real-time PCR.
Molecular and cellular probes - 1 Jan 2000
Sheng Wang-Huei, Lin Yu-Chi, Wang Jann-Tay, Chen Yee-Chun, Chang Shan-Chwen, Hsia Ko-Chiang, Wu Ruei-Jiuan, Li Shu-Ying
Abstract excerpt
Ciprofloxacin-resistant (CipR) Acinetobacter spp. was associated with a mutation in quinolone resistance-determining region (QRDR) of gyrA gene from Ser83 to Leu83. A total of 54 Acinetobacter baumannii, 11 A. genospecies 3, and 17 A. genospecies 13TU clinical isolates were determined for ciprofloxacin susceptibility and their QRDR sequenced. Most of A. baumannii were CipR and had a mutated QRDR of gyrA gene, and...
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