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Article

Development of a pyrosequencing assay for rapid assessment of quinolone resistance in Acinetobacter baumannii isolates.

Journal of microbiological methods - 1 Jul 2011

Deccache Yann, Irenge Léonid M, Savov Encho, Ariciuc Mihaela, Macovei Alexandra, Trifonova Angelina, Gergova Ivanka, Ambroise Jérôme, Vanhoof Raymond, Gala Jean-Luc

Abstract excerpt

Rapid and reliable assessment of Acinetobacter baumannii resistance to quinolones was successfully achieved through pyrosequencing of the gyrA and parC quinolone-resistance determining regions. A strong correlation was found between quinolone resistance and mutations in gyrA codon 83 and/or in the parC gene (codons 80 or 84). Absence of QRDR mutations was associated with susceptibility to quinolones.

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PMID: 21514328
DOI: 10.1016/j.mimet.2011.04.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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