Article
A mismatch amplification mutation assay for specific detection of ciprofloxacin-resistant Neisseria meningitidis.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 May 2023
Ota Yusuke, Okada Reina, Takahashi Hideyuki, Saito Ryoichi
Abstract excerpt
Meningococcal chemoprophylaxis for people in close contact with patients with invasive meningococcal disease (IMD) is necessary for preventing the spread of Neisseria meningitidis. Ciprofloxacin (CIP) is commonly used to treat IMD. However, CIP-resistant N. meningitidis isolates have rapidly evolved worldwide; therefore, rapid and accurate detection of CIP-resistant N. meningitidis is essential. We developed a...
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