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Article

COX-2 polymorphisms and the risk for head and neck cancer in white patients.

Head & neck - 1 Jul 2009

Peters Wilbert H M, Lacko Martin, Te Morsche Rene H M, Voogd Adri C, Oude Ophuis Michael B, Manni Johannes J

Abstract excerpt

BACKGROUND: Cyclooxygenase-2 (COX-2) is an enzyme involved in the synthesis of prostaglandins and thromboxanes, which are regulators of processes such as inflammation, cell proliferation, and angiogenesis, all relevant for cancer development. We investigated whether functional genetic polymorphisms in COX-2 may have a risk-modifying effect on head and neck carcinogenesis. METHODS: Blood from 431 white patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19280666
DOI: 10.1002/hed.21058

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