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Article

COX-2 rs689466, rs5275, and rs20417 polymorphisms and risk of head and neck squamous cell carcinoma: a meta-analysis of adjusted and unadjusted data.

BMC cancer - 13 Jul 2016

Leng Wei-Dong, Wen Xiu-Jie, Kwong Joey S W, Huang Wei, Chen Jian-Gang, Zeng Xian-Tao

Abstract excerpt

BACKGROUND: Numerous case-control studies have been performed to investigate the association between three cyclooxygenase-2 (COX-2) polymorphisms (rs20417 (-765G > C), rs689466 (-1195G > A), and rs5275 (8473 T > C)) and the risk of head and neck squamous cell carcinoma (HNSCC). However, the results were inconsistent. Therefore, we conducted this meta-analysis to investigate the association. METHODS: We searched...

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Share to Carcinoma, Squamous Cell
Share to Cyclooxygenase 2
Share to Genetic Predisposition to Disease
Share to Head and Neck Neoplasms
Share to Odds Ratio
Share to Polymorphism, Single Nucleotide
Share to Risk Factors
Share to Squamous Cell Carcinoma of Head and Neck

Source

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Identifiers

PMID: 27412115
DOI: 10.1186/s12885-016-2535-3
PMCID: PMC4942952

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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