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Article

Bone mass effects of a Smad6 gene polymorphism in Japanese postmenopausal women.

Journal of bone and mineral metabolism - 1 Jan 2009

Urano Tomohiko, Shiraki Masataka, Usui Takahiko, Sasaki Noriko, Ouchi Yasuyoshi, Inoue Satoshi

Abstract excerpt

Smad6 plays pivotal roles in the negative regulation of transforming growth factor beta (TGFbeta) family signaling as one of the feedback molecules. Here, we analyzed whether the human Smad6 gene is involved in the regulation of bone mass, using association analysis between bone mineral density (BMD) and single-nucleotide polymorphism (SNP) in the Smad6 gene. Association of an SNP at IVS3+26115A>C (intron 3,...

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Identifiers

PMID: 19277452
DOI: 10.1007/s00774-009-0068-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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