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Article

Characterisation of Early Mucosal and Neuronal Lesions Following Shigella flexneri Infection in Human Colon

5 Mar 2009

Abstract excerpt

BACKGROUND: Shigella, an enteroinvasive bacteria induces a major inflammatory response responsible for acute rectocolitis in humans. However, early effect of Shigella flexneri (S. flexneri) infection upon the human mucosa and its microenvironement, in particular the enteric nervous system, remains currently unknown. Therefore, in this study, we sought to characterize ex vivo the early events of shigellosis in a...

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PMID: 19274103
DOI: 10.1371/journal.pone.0004713

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