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Article

Protease‐dependent excitation of nodose ganglion neurons by commensal gut bacteria

5 Mar 2020

Abstract excerpt

Key points The vagus nerve has been implicated in mediating behavioural effects of the gut microbiota on the central nervous system. This study examined whether the secretory products of commensal gut bacteria can modulate the excitability of vagal afferent neurons with cell bodies in nodose ganglia. Cysteine proteases from commensal bacteria increased the excitability of vagal afferent neurons via activation of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32134496
DOI: 10.1113/jp279075

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