Article
An integrated view of protein evolution.
Nature reviews. Genetics - 1 May 2006
Pál Csaba, Papp Balázs, Lercher Martin J
Abstract excerpt
Why do proteins evolve at different rates? Advances in systems biology and genomics have facilitated a move from studying individual proteins to characterizing global cellular factors. Systematic surveys indicate that protein evolution is not determined exclusively by selection on protein structure and function, but is also affected by the genomic position of the encoding genes, their expression patterns, their...
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