Article
Breast cancer risk associated with polymorphisms of IL-1RN and IL-4 gene in Indian women.
Oncology research - 1 Jan 2009
Konwar Rituraj, Chaudhary Preeti, Kumar Sandeep, Mishra Deepti, Chattopadhyay Naibedya, Bid Hemant Kumar
Abstract excerpt
Interleukins and cytokines are important regulator of the aetio-pathogenesis of the majority of cancers. Mechanistic role of IL-1RN and IL-4, particularly in breast carcinogenesis, is well documented. However, the role of polymorphisms of IL-1RN and IL-4 combinations associated with risk of breast cancer is not reported. The IL-1RN and IL-4 gene polymorphisms were genotyped with VNTR-PCR in 100 patients (benign...
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