Article
Sequence variation in the mitochondrial gene cytochrome c oxidase subunit I and prostate cancer in African American men.
The Prostate - 15 Jun 2009
Ray Anna M, Zuhlke Kimberly A, Levin Albert M, Douglas Julie A, Cooney Kathleen A, Petros John A
Abstract excerpt
BACKGROUND: Previous studies have found associations between mitochondrial DNA (mtDNA) mutations and several cancer types. Recently, we found that mutations in the mtDNA gene cytochrome c oxidase subunit 1 (COI) were both linked to and associated with prostate cancer (PCa) in Caucasian men. Here we examine the association between COI mutations and PCa in African American men. METHODS: The entire COI gene was...
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