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North American White Mitochondrial Haplogroups in Prostate and Renal Cancer

8 Jan 2006

Abstract excerpt

PURPOSE: While the mitochondrion is known to be a key mediator of apoptosis, there has been little inquiry into the inheritance pattern of mitochondria in patients with cancer. We compared the mtDNA haplotype in patients with prostate and renal cancer to that in controls to determine if there is an association between mitochondrial genotype and cancer. MATERIALS AND METHODS: Haplotyping was performed using...

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PMID: 16406974
DOI: 10.1016/s0022-5347(05)00163-1

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