Article
Sequence variants of alpha-methylacyl-CoA racemase are associated with prostate cancer risk.
Cancer research - 15 Nov 2002
Zheng Siqun L, Chang Bao-li, Faith Dennis A, Johnson Jill R, Isaacs Sarah D, Hawkins Gregory A, Turner Aubrey, Wiley Kathy E, Bleecker Eugene R, Walsh Patrick C, Meyers Deborah A, Isaacs William B, Xu Jianfeng
Abstract excerpt
The enzyme alpha-methylacyl-CoA racemase (AMACR) plays an important role in peroxisomal beta-oxidation of branched-chain fatty acid and therefore is relevant to carcinogenesis. The involvement of AMACR in prostate cancer (CaP) is implicated by the recent observation that expression of AMACR is co...
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