Article
Genetic variation and population substructure in outbred CD-1 mice: implications for genome-wide association studies.
PloS one - 1 Jan 2009
Aldinger Kimberly A, Sokoloff Greta, Rosenberg David M, Palmer Abraham A, Millen Kathleen J
Abstract excerpt
Outbred laboratory mouse populations are widely used in biomedical research. Since little is known about the degree of genetic variation present in these populations, they are not widely used for genetic studies. Commercially available outbred CD-1 mice are drawn from an extremely large breeding population that has accumulated many recombination events, which is desirable for genome-wide association studies. We...
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