Article
Decreased NK cell frequency and function is associated with increased risk of KIR3DL allele polymorphism in simian immunodeficiency virus-infected rhesus macaques with high viral loads.
Journal of immunology (Baltimore, Md. : 1950) - 15 Mar 2009
Bostik Pavel, Kobkitjaroen Jaruda, Tang Weining, Villinger Francois, Pereira Lara E, Little Dawn M, Stephenson Susan T, Bouzyk Mark, Ansari Aftab A
Abstract excerpt
NK cells have been established as an important effector of innate immunity in a variety of viral infections. In HIV-1 infection in humans, alterations of NK cell function, frequency, and expression of various NK receptors have been reported to be associated with differential dynamics of disease p...
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