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Article

MEP1A allele for meprin A metalloprotease is a susceptibility gene for inflammatory bowel disease.

Mucosal immunology - 1 May 2009

Banerjee S, Oneda B, Yap L M, Jewell D P, Matters G L, Fitzpatrick L R, Seibold F, Sterchi E E, Ahmad T, Lottaz D, Bond J S

Abstract excerpt

The MEP1A gene, located on human chromosome 6p (mouse chromosome 17) in a susceptibility region for inflammatory bowel disease (IBD), encodes the alpha-subunit of metalloproteinase meprin A, which is expressed in the intestinal epithelium. This study shows a genetic association of MEP1A with IBD in a cohort of ulcerative colitis (UC) patients. There were four single-nucleotide polymorphisms in the coding region...

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Identifiers

PMID: 19262505
DOI: 10.1038/mi.2009.3
PMCID: PMC2670347

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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