Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Overexpression of eukaryotic initiation factor 4E (eIF4E) and its clinical significance in lung adenocarcinoma.

Lung cancer (Amsterdam, Netherlands) - 1 Nov 2009

Wang Rui, Geng Jian, Wang Jing-hua, Chu Xiao-yuan, Geng Huai-cheng, Chen Long-bang

Abstract excerpt

BACKGROUND: Eukaryotic initiation factor 4E (eIF4E), an important regulator of translation, plays important roles in tumor transformation, progression and metastasis. However, the clinical significance of eIF4E expression in lung adenocarcinoma (AdC) remains unclear. The aim of this study was to explore the expression of eIF4E gene in lung adenocarcinoma cell lines and tissues, and to investigate its relationship...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Line, Tumor

Share to Eukaryotic Initiation Factor-4E

Share to Gene Expression

Share to Genetic Predisposition to Disease

Share to Lung Neoplasms

Share to RNA, Messenger

Source

Identifiers

PMID: 19261348
DOI: 10.1016/j.lungcan.2009.02.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Overexpression of eukaryotic initiation factor 4E (eIF4E) and its clinical significance in lung adenocarcinoma.PMID 19261348Read ↗

Overexpression of p-Akt, p-mTOR and p-eIF4E proteins associates with metastasis and unfavorable prognosis in non-small cell lung cancerSemantic proximity Read ↗

Proteomic analysis of eIF-5A in lung adenocarcinomas.Semantic proximity Read ↗

Phosphorylated eukaryotic translation initiation factor 4 (eIF4E) is elevated in human cancer tissuesSemantic proximity Read ↗

Eukaryotic translation initiation factor 5A in the pathogenesis of cancers (Review)Semantic proximity Read ↗

Targeting the Eukaryotic Translation Initiation Factor 4E for Cancer TherapySemantic proximity Read ↗

Unlocking the role of EIF5A: A potential diagnostic marker regulating the cell cycle and showing negative correlation with immune infiltration in lung adenocarcinomaSemantic proximity Read ↗

Targeting the eIF4F translation initiation complex for cancer therapySemantic proximity Read ↗

Effect of shRNA-Mediated Knockdown EBF1 Gene Expression on the Proliferation of Lung Cancer Cell Line A549 In Vitro and In VivoSemantic proximity Read ↗

UBE2S promotes the proliferation and survival of human lung adenocarcinoma cellsSemantic proximity Read ↗

Clinical significance of elongation factor-1 delta mRNA expression in oesophageal carcinomaSemantic proximity Read ↗

Eukaryotic translation initiation factor 4E (eIF4E) expression is associated with breast cancer tumor phenotype and predicts survival after anthracycline chemotherapy treatment.Semantic proximity Read ↗

4E-BP1, a multifactor regulated multifunctional proteinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.