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Differential stepwise evolution of SARS coronavirus functional proteins in different host species

5 Mar 2009

Abstract excerpt

BACKGROUND: SARS coronavirus (SARS-CoV) was identified as the etiological agent of SARS, and extensive investigations indicated that it originated from an animal source (probably bats) and was recently introduced into the human population via wildlife animals from wet markets in southern China. Previous studies revealed that the spike (S) protein of SARS had experienced adaptive evolution, but whether other...

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PMID: 19261195
DOI: 10.1186/1471-2148-9-52

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