Article
A beta-catenin-dependent Wnt pathway mediates anteroposterior axon guidance in C. elegans motor neurons.
PloS one - 1 Jan 2009
Maro Géraldine S, Klassen Matthew P, Shen Kang
Abstract excerpt
BACKGROUND: Wnts are secreted glycoproteins that regulate diverse aspects of development, including cell proliferation, cell fate specification and differentiation. More recently, Wnts have been shown to direct axon guidance in vertebrates, flies and worms. However, little is known about the intracellular signaling pathways downstream of Wnts in axon guidance. METHODOLOGY/PRINCIPAL FINDINGS: Here we show that the...
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