Article
Interleukin-7 receptor-alpha gene polymorphisms in bone marrow transplant recipients.
Molecular biology reports - 1 Jan 2010
Azarpira Negar, Dehghani Mehdi, Aghdaie Mahdokth H, Darai Masumeh
Abstract excerpt
Graft-versus-host disease is the main complication after hematopoietic stem cells transplantation (HSCT). Non-HLA genotypes, such as cytokines, have been investigated for their potential roles in the occurrence and severity of GVHD as well as for their contribution to overall transplant-related mortality and survival. IL-7 which is secreted by bone marrow stromal cells plays an important role in the development...
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