Article
Vaccination of guinea pigs using mce operon mutants of Mycobacterium tuberculosis.
Vaccine - 10 Jun 2011
Obregón-Henao Andrés, Shanley Crystal, Bianco María Verónica, Cataldi Angel A, Basaraba Randall J, Orme Ian M, Bigi Fabiana
Abstract excerpt
The limited efficacy of the BCG vaccine for tuberculosis, coupled with emerging information suggesting that it is poorly protective against newly emerging strains of Mycobacterium tuberculosis such as the W-Beijing isolates, makes it paramount to search for more potent alternatives. One such class of candidates is attenuated mutants derived from M. tuberculosis itself. We demonstrate here, in an initial short...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
