Article

Characterization of a novel intratracheal aerosol challenge model of <i>Brucella melitensis</i> in guinea pigs

2018-10-30

Abstract excerpt

B. melitensis is considered the most virulent of the Brucella species, and a need exists for an improved laboratory animal model of infection that mimics natural transmission and disease. Guinea pigs are highly susceptible to infection with Brucella spp. and develop a disease syndrome that mimics natural disease after aerosol inoculation. Intratracheal inoculation is a targeted means of generating aerosols that...

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Literature Corpus work: 3e2c50d6-6658-5c24-9c0d-f4e60285acef
DOI: 10.1101/457184

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