Article
Indolocarbazole antitumour compounds by combinatorial biosynthesis.
Current opinion in chemical biology - 1 Apr 2009
Salas José A, Méndez Carmen
Abstract excerpt
The indolocarbazoles constitute a family of natural products with potential therapeutic applications in the treatment of cancer and neurodegenerative disorders. Members of this family are either potent stabilizers of topoisomerase I-DNA covalent complex or potent inhibitors of protein kinases. Re...
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