Article

Elucidation and derivatisation of bisindole biosynthesis pathways

2019-01-01

Abstract excerpt

Bisindole natural products encompass the well-studied indolocarbazoles, such as rebeccamycin and staurosporine, among other minor classes including indolotryptolines and bisindolylpyrroles. Bisindole biosynthesis starts from L-tryptophan and forms highly aromatic bisindole scaffolds in a series of biosynthetic steps, which are catalysed by various core scaffold formation and tailoring enzymes that work in tandem t...

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Literature Corpus work: cdb4ca7c-c7e8-5ddc-8bd5-48b39f606bc9
DOI: 10.25560/84717

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