Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HU and IHF: similarities and differences. In Escherichia coli, the lack of HU is not compensated for by IHF.

Research in microbiology - 1 Jan 2000

Boubrik F, Bonnefoy E, Rouvière-Yaniv J

Abstract excerpt

HU is one of the most abundant DNA binding proteins in Escherichia coli. Like the histones, HU is able to condense DNA in vitro and to introduce negative super-coiling in covalently closed circular, relaxed DNA molecules in the presence of topoisomerase I. HU is well conserved in all prokaryotes but surprisingly, it is also homologous to another E. coli DNA-binding protein, IHF. Contrary to HU, IHF shows sequence...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to DNA, Bacterial
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Escherichia coli

Share to Integration Host Factors

Share to Mutation

Share to Plasmids

Share to Transformation, Genetic

Source

Identifiers

PMID: 1925023
DOI: 10.1016/0923-2508(91)90036-a

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HU and IHF: similarities and differences. In Escherichia coli, the lack of HU is not compensated for by IHF.PMID 1925023Read ↗

Requirement of integration host factor (IHF) for growth of Escherichia coli deficient in HU protein.Semantic proximity Read ↗

Participation of the histone-like protein HU and of IHF in minichromosomal maintenance in Escherichia coli.Semantic proximity Read ↗

Escherichia coli HU protein suppresses DNA-gyrase-mediated illegitimate recombination and SOS induction.Semantic proximity Read ↗

Heat shock-induced excessive relaxation of DNA in Escherichia coli mutants lacking the histone-like protein HU.Semantic proximity Read ↗

Increased sensitivity to gamma irradiation in bacteria lacking protein HU.Semantic proximity Read ↗

Selected phenotypes of ihf mutants of Escherichia coli.Semantic proximity Read ↗

Coordination of genomic structure and transcription by the main bacterial nucleoid-associated protein HU.Semantic proximity Read ↗

The HU regulon is composed of genes responding to anaerobiosis, acid stress, high osmolarity and SOS induction.Semantic proximity Read ↗

Roles of Escherichia coli histone-like protein HU in DNA replication: HU-beta suppresses the thermosensitivity of dnaA46ts.Semantic proximity Read ↗

Genetic and biochemical analysis of the integration host factor of Escherichia coli.Semantic proximity Read ↗

Cross-talk between topoisomerase I and HU in Escherichia coli.Semantic proximity Read ↗

Histone-like protein HU and bacterial DNA topology: suppression of an HU deficiency by gyrase mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.