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Article

Increased sensitivity to gamma irradiation in bacteria lacking protein HU.

Proceedings of the National Academy of Sciences of the United States of America - 25 Apr 1995

Boubrik F, Rouviere-Yaniv J

Abstract excerpt

The heterodimeric HU protein, isolated from Escherichia coli, is associated with the bacterial nucleoid and shares some properties with both histones and HMG proteins. It is the prototype of small bacterial DNA binding proteins with a pleiotropic role in the cell. HU participates in several biological processes like cell division, initiation of DNA replication, transposition, and other biochemical functions. We...

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Identifiers

PMID: 7732012
DOI: 10.1073/pnas.92.9.3958
PMCID: PMC42081

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Related research

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Increased sensitivity to gamma irradiation in bacteria lacking protein HU.PMID 7732012Read ↗

Escherichia coli HU protein suppresses DNA-gyrase-mediated illegitimate recombination and SOS induction.Semantic proximity Read ↗

Escherichia coli strains lacking protein HU are UV sensitive due to a role for HU in homologous recombination.Semantic proximity Read ↗

HU-1 mutants of Escherichia coli deficient in DNA binding.Semantic proximity Read ↗

Roles of Escherichia coli histone-like protein HU in DNA replication: HU-beta suppresses the thermosensitivity of dnaA46ts.Semantic proximity Read ↗

Escherichia coli HU protein has a role in the repair of abasic sites in DNA.Semantic proximity Read ↗

Coordination of genomic structure and transcription by the main bacterial nucleoid-associated protein HU.Semantic proximity Read ↗

The HU regulon is composed of genes responding to anaerobiosis, acid stress, high osmolarity and SOS induction.Semantic proximity Read ↗

Histone-like protein HU is required for recA gene-dependent DNA repair and SOS induction pathways in UV-irradiated Escherichia coli.Semantic proximity Read ↗

The Escherichia coli histone-like protein HU affects DNA initiation, chromosome partitioning via MukB, and cell division via MinCDE.Semantic proximity Read ↗

Histone-like protein HU and bacterial DNA topology: suppression of an HU deficiency by gyrase mutations.Semantic proximity Read ↗

HU and IHF: similarities and differences. In Escherichia coli, the lack of HU is not compensated for by IHF.Semantic proximity Read ↗

Heat shock-induced excessive relaxation of DNA in Escherichia coli mutants lacking the histone-like protein HU.Semantic proximity Read ↗

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