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Article

Characterization of Escherichia coli mutants with altered ploidy.

Research in microbiology - 1 Jan 2000

Trun N J, Gottesman S

Abstract excerpt

We describe the isolation and characterization of new mutants in the cell cycle of Escherichia coli. The mutants were selected as gain of function mutants that are able to maintain more than the normal number of chromosomes. Our increased ploidy mutants were isolated as resistant to camphor vapours, which selects for cells with more chromosomes than normal. The mutants (called mbr for moth-ball-resistant) map to...

Topics

Camphor
Cell Cycle
Cell Division
DNA Replication
Drug Resistance, Microbial
Escherichia coli
Genes, Bacterial
Genes, Dominant
Mutation
Ploidies
Replicon

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1925019
DOI: 10.1016/0923-2508(91)90030-e

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1925019-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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