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Article

Hap4 is not essential for activation of respiration at low specific growth rates in Saccharomyces cerevisiae.

The Journal of biological chemistry - 5 May 2006

Raghevendran Vijayendran, Patil Kiran Raosaheb, Olsson Lisbeth, Nielsen Jens

Abstract excerpt

In Saccharomyces cerevisiae, the heme-activated protein complex Hap2/3/4/5 plays a major role in the transcription of genes involved in respiration. Thus, overexpression of HAP4 has been shown to result in a 10% increase in the respiratory capacity. Here the physiology of a HAP4-deleted S. cerevisiae strain was investigated, and we found that the hap4delta S. cerevisiae exhibited poor growth on ethanol, although...

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PMID: 16522629
DOI: 10.1074/jbc.M512972200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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