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Article

FBXW7 and NOTCH1 mutations in childhood T cell acute lymphoblastic leukaemia and T cell non-Hodgkin lymphoma.

British journal of haematology - 1 Apr 2009

Park Myoung-Ja, Taki Tomohiko, Oda Megumi, Watanabe Tomoyuki, Yumura-Yagi Keiko, Kobayashi Ryoji, Suzuki Nobuhiro, Hara Junichi, Horibe Keizo, Hayashi Yasuhide

Abstract excerpt

Mutation analysis of FBXW7 and NOTCH1 genes was performed in 55 T cell acute lymphoblastic leukaemia (T-ALL) and 14 T cell non-Hodgkin lymphoma (T-NHL) patients who were treated on the Japan Association of Childhood Leukaemia Study (JACLS) protocols ALL-97 and NHL-98. FBXW7 and/or NOTCH1 mutations were found in 22 (40.0%) of 55 T-ALL and 7 (50.0%) of 14 T-NHL patients. FBXW7 mutations were found in 8 (14.6%) of...

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Share to Chromatography, High Pressure Liquid
Share to Disease-Free Survival

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to F-Box Proteins

Share to F-Box-WD Repeat-Containing Protein 7

Share to Gene Expression Regulation, Leukemic

Share to Lymphoma, T-Cell

Share to Precursor T-Cell Lymphoblastic Leukemia-Lymphoma

Share to Receptor, Notch1

Source

Identifiers

PMID: 19245433
DOI: 10.1111/j.1365-2141.2009.07607.x

Genes

NOTCH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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FBXW7 and NOTCH1 mutations in childhood T cell acute lymphoblastic leukaemia and T cell non-Hodgkin lymphoma.PMID 19245433Read ↗

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