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Article

ApoE alleles, depression and positive affect in multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Mar 2009

Julian L J, Vella L, Frankel D, Minden S L, Oksenberg J R, Mohr D C

Abstract excerpt

BACKGROUND: The role of apolipoprotein E (ApoE) alleles has received recent attention in depressive disorders, the ApoE epsilon4 conferring greater risk for poorer outcomes, and the ApoE epsilon2 allele providing some protective effects. Depression is common in multiple sclerosis (MS) and the role of ApoE alleles is unknown. AIMS: To evaluate ApoE alleles in relation to symptoms of depression in a cohort of...

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Identifiers

PMID: 19244396
DOI: 10.1177/1352458508099478
PMCID: PMC3045528

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