Article
APOE genotype predicts depression in women with Alzheimer's disease: a retrospective study.
International journal of geriatric psychiatry - 1 Jun 2008
Delano-Wood Lisa, Houston Wes S, Emond Jennifer A, Marchant Natalie L, Salmon David P, Jeste Dilip V, Thal Leon J, Bondi Mark W
Abstract excerpt
OBJECTIVE: The association between the APOE epsilon4 allele and depression was investigated in a retrospective study of 323 AD patients. METHODS: Patients were divided into demographically comparable groups based on the presence or absence of depression. RESULTS: Results showed that the frequency of APOE epsilon4 allele was significantly higher in the depressed vs non-depressed AD patients (72% and 58%,...
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