Murine models of cutaneous involvement in lupus erythematosus.

Abstract excerpt

Skin manifestations of lupus erythematosus (LE) are common and are a significant source of morbidity. Lupus-specific skin disease includes chronic cutaneous lupus, subacute cutaneous lupus and acute cutaneous lupus. These conditions have in common a lichenoid tissue reaction. The best-characterized mouse model of spontaneous onset lupus-like skin disease is the MRL/lpr mouse. We review features of this mouse...

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