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Article

Serotype chimeric and fiber-mutated adenovirus Ad5/19p-HIT for targeting renal cancer and untargeting the liver.

Human gene therapy - 1 Jun 2009

Diaconu Iulia, Denby Laura, Pesonen Sari, Cerullo Vincenzo, Bauerschmitz Gerd J, Guse Kilian, Rajecki Maria, Dias João D, Taari Kimmo, Kanerva Anna, Baker Andrew H, Hemminki Akseli

Abstract excerpt

Despite some advances, patients with advanced renal cell carcinoma (RCC) cannot usually be cured. Alteration of the natural tropism of adenoviruses may permit more specific gene transfer to target tissues. The aim of this study was to use novel targeting moieties for adenoviral gene therapy of RC...

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PMID: 19239383
DOI: 10.1089/hum.2008.108

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19239383-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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