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Article

WDTC1, the ortholog of Drosophila adipose gene, associates with human obesity, modulated by MUFA intake.

Obesity (Silver Spring, Md.) - 1 Mar 2009

Lai Chao-Qiang, Parnell Laurence D, Arnett Donna K, García-Bailo Bibiana, Tsai Michael Y, Kabagambe Edmond K, Straka Robert J, Province Michael A, An Ping, Borecki Ingrid B, Tucker Katherine L, Ordovás José M

Abstract excerpt

Adipose (adp) is an obesity gene in Drosophila and mice with crucial functions in fat metabolism. We investigated the correlation between genetic variation of the WDTC1 locus, the ortholog of adp, and human obesity. Five WDTC1 single-nucleotide polymorphisms (SNPs) were genotyped in 935 and 1,115 adults of two ethnically diverse US populations. In the Boston Puerto Rican population, we demonstrated that two WDTC1...

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Identifiers

PMID: 19238144
DOI: 10.1038/oby.2008.561
PMCID: PMC2874970

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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