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Article

Genetic interaction of DGAT2 and FAAH in the development of human obesity.

Endocrine - 1 May 2017

Ning Tinglu, Zou Yaoyu, Yang Minglan, Lu Qianqian, Chen Maopei, Liu Wen, Zhao Shaoqian, Sun Yingkai, Shi Juan, Ma Qinyun, Hong Jie, Liu Ruixin, Wang Jiqiu, Ning Guang

Abstract excerpt

PURPOSE: DGAT2 is the critical catalyzing enzyme for triglyceride biosynthesis, and excess triglyceride accumulation in fat tissues is a fundamental process for obesity. Mutations in DGAT2 or other genes interacting with DGAT2 associated with adiposity have not been reported in human to date. METHODS: DGAT2 mutation was identified based on our in-home database-exome sequencing 227 young obese subjects (body-mass...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28243972
DOI: 10.1007/s12020-017-1261-1

Genes

DGAT2
FAAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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