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Article

Comparative docking studies of CYP1b1 and its PCG-associated mutant forms.

Journal of biosciences - 1 Dec 2008

Achary Malkaram Sridhar, Nagarajam Hampapathalu Adimurthy

Abstract excerpt

Molecular docking has been used to compare and contrast the binding modes of oestradiol with the wild-type and some disease-associated mutant forms of the human CYP1b1 protein.The receptor structures used for docking were derived from molecular dynamics simulations of homology-modelled structures. Earlier studies involving molecular dynamics and principal component analysis indicated that mutations could have a...

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PMID: 19179758
DOI: 10.1007/s12038-008-0090-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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