Article
Association between genetic variants in myosin IXB and Crohn's disease.
Inflammatory bowel diseases - 1 Jul 2009
Cooney Rachel, Cummings J R Fraser, Pathan Saad, Beckly John, Geremia Alessandra, Hancock Laura, Guo Changcun, Morris Andrew, Jewell Derek P
Abstract excerpt
BACKGROUND: Genetic variation in myosin IXB (MYO9B) was found to be associated with ulcerative colitis (UC) in a recent collaborative study. A nonsynonymous single nucleotide polymorphism (SNP) rs1545620 at the 3' end of the gene was found to be significantly associated with UC and weakly associated with Crohn's disease (CD). The aim of our current study was to replicate these findings in an independent UC cohort...
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