Article
Association analysis of myosin IXB and type 1 diabetes.
Human immunology - 1 Jun 2010
Persengiev Stephan, Koeleman Bobby P C, Downes Kate, Valdigem Gustavo, van der Slik Arno R, Eerligh Peter, Monsuur Alienke, Bruining G Jan, Wijmenga Cisca, Todd John A, Roep Bart O, Alizadeh Behrooz Z
Abstract excerpt
To date, seven studies have provided evidence for an association between the gene encoding for myosin IXB (MYO9B) and celiac disease (CD), and inflammatory bowel diseases, including single nucleotide polymorphisms (SNPs) rs2305767, rs1457092, and rs2305764. We investigated whether MYO9B is associated with T1D. The three SNPs were genotyped in Dutch samples from 288 T1D patients and 1615 controls. The A allele of...
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